Cor pulmonale in the Pierre Robin syndrome.

سندرم پیرروبین ( THE PIERRE ROBIN SYNDROME )

Role of SOX9 in the Etiology of Pierre-Robin Syndrome

Objective(s:Cleft lip/palate are common congenital anomalies, affecting approximately 2/1000 live births. Pierre Robin Sequence is a subgroup of the cleft palate population. Chromosomal abnormalities near the SOX9 gene disrupt the regulation of this gene and prevent the SOX9 protein from properly controlling the development of facial structures, which leads to isolated PRS. The present study wa...

Cor Pulmonale

ar+ Unsual obstruction is found in the pulmonary adH^' Electrocardiography in spite of many ari!^ ?ns ^ea<^s does no^ appear to have "ed much to our knowledge. Two new procedures, essentially clinical, have ^1 yet been made use of in unravelling the ystery of the genesis of Cor, Pulmonale. They of*(1) The removal of a lung. The reduction ? the vascular bed is not likely to be less than e one ca...

The Robin anomalad (Pierre Robin syndrome)--a follow up study.

During a 10-year period 55 patients with the Robin anomalad were admitted to the Liverpool Regional Cleft Palate Units. Fourteen (25%) children died. All deaths were within 3 months of birth. Congenital abnormalities other than mandibular retrognathia and cleft palate were present in 14 (26%) children. Peripheral limb defects were particularly common. Thirty children were recalled and reviewed ...

Cor pulmonale revisited.

I remember first being introduced to the term cor pulmonale in medical school, which was used to describe right heart failure due to chronic lung disease, and I still have a mental picture of the typical patient as a former heavy smoker, dyspneic at rest, and cyanotic with neck vein distention and lower extremity edema. However, even early catheterization studies of the normal and diseased huma...